The building that now houses the Happy Isles Art & Nature Center was originally constructed in 1927. The state of California operated a fish hatchery in the building to stock lakes and streams for recreational fishing. The hatchery was shut down in 1956 and the National Park Service took ownership of the building.

In subsequent years, the building and surrounding area was developed into a visitor information center, and eventually the art and nature center it is today.

The building was constructed during the rustic era and displays numerous features similar to other rustic park buildings such as the museum and administration building in the village. The walls of the building are inlaid with river rocks and several aspects feature rough-hewn log accents.